In the 19th century, craftsmen who made hats were known to be excitable and irrational, as well as to tremble with palsy and mix up their words. Such behavior gave rise to the familiar expression 'X'. The disorder, called 'Y' shakes, was caused by chronic mercury poisoning from the solution used to treat the felt. Attacking the central nervous system, the toxin led to behavioral symptoms.
Id 'X' & 'Y'...
'X'-Mad as a hatter,'Y'-Hatter's syndrome
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